Bruker DPX 400 MHz

Of the two Open Access NMR instruments, the DPX400 is superior for performing heteronuclear direct detection, as the probe for this instrument has optimized sensitivity for heteronuclei. Therefore, if you have a limited amount of sample (see Sample Requirements for Experiments in NMR for the minimum amount of sample which is required in order for each of the above experiments to succeed) you will get much better results from running your 1D-NMR ¹³C, DEPTQ and DEPT-135 experiments on the DPX400, in preference to the Nano400. Conversely, 2D-NMR experiments involving direct observation of proton, such as edited-HSQC, HMBC, COSY and NOESY, will give better results on the DPX400, if only a small amount of sample is available. Very small amounts of sample, which cannot be run in a reasonable time on either of the Open Access NMR instruments, can be submitted to the Internal NMR Service (either the Bruker Avance III 500 MHz or the AV700 NMR instruments) for acquisition by the NMR Staff.