{"id":1894,"date":"2017-04-26T16:27:36","date_gmt":"2017-04-26T15:27:36","guid":{"rendered":"https:\/\/research.reading.ac.uk\/cinn\/?p=1894"},"modified":"2024-09-09T16:43:25","modified_gmt":"2024-09-09T15:43:25","slug":"motivational-disorders-in-brain-conditions","status":"publish","type":"post","link":"https:\/\/research.reading.ac.uk\/cinn\/motivational-disorders-in-brain-conditions\/","title":{"rendered":"Motivational Disorders in Brain Conditions"},"content":{"rendered":"<p><a title=\"Dr Ciara McCabe\" href=\"http:\/\/reading.ac.uk\/cinn\/who-we-are\/cinn-staff\/dr-ciara-mccabe\/\" data-id=\"1155\">Professor Ciara McCabe<\/a>\u00a0was included in a write up by\u00a0The Dana Foundation\u00a0on the BNA Festival of Neuroscience.<\/p>\n<p>Discussing research looking at how disorders of motivation affect a significant minority of people with neurodegenerative disease, stroke or traumatic injury, and those suffering neuropsychiatric conditions.<\/p>\n<p>Ciara talked about her research into the reward\u00a0processing in the brains of people with depression.<\/p>\n<p>\u201cDepression is maintained by a negative bias, or an over-processing of negative information about the self or environment,\u201d McCabe said. \u201cThe psychological and drug treatments we have only work in about 30-50 percent of people, and one of the reasons for that could be that there are other symptoms that aren&#8217;t being targeted.\u201d [See:\u00a0The Link Between Depression, Sleep, and Stress\u00a0and\u00a0Does Depression Change the Way People Perceive the World?]<\/p>\n<p>One of these is anhedonia, or an inability to experience pleasure and rewards, one of the two main criteria for a diagnosis of depression. A better understanding of reward processing in depression could therefore lead to novel therapies and treatments.<\/p>\n<p>Earlier this year, McCabe and her colleagues published preliminary evidence that differences in reward processing could identify adolescents at risk of developing full-blown depression. They recruited 33 adolescents with depressive symptoms, 16 deemed to be at high risk, as determined by a mood questionnaire, and 17 at low risk, and scanned their brains while they first viewed images of, and then ate, pleasant and unpleasant foods.<\/p>\n<p>They found that those at high risk of developing depression had\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28093022\">blunted brain responses<\/a>\u00a0when viewing and eating both types of food, suggesting that they both underestimate the value of anticipated rewards and are less sensitive to rewards they receive.<\/p>\n<p>\u201cAnticipation of reward seems to be a marker for depression,\u201d said McCabe. \u201cIf we can decipher how the different types of reward processing are altered, maybe interventions could target them.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Professor Ciara McCabe\u00a0was included in a write up by\u00a0The Dana Foundation\u00a0on the BNA Festival of Neuroscience. Discussing research looking at how disorders of motivation affect a significant minority of people&#8230;<a class=\"read-more\" href=\"&#104;&#116;&#116;&#112;&#115;&#58;&#47;&#47;&#114;&#101;&#115;&#101;&#97;&#114;&#99;&#104;&#46;&#114;&#101;&#97;&#100;&#105;&#110;&#103;&#46;&#97;&#99;&#46;&#117;&#107;&#47;&#99;&#105;&#110;&#110;&#47;&#109;&#111;&#116;&#105;&#118;&#97;&#116;&#105;&#111;&#110;&#97;&#108;&#45;&#100;&#105;&#115;&#111;&#114;&#100;&#101;&#114;&#115;&#45;&#105;&#110;&#45;&#98;&#114;&#97;&#105;&#110;&#45;&#99;&#111;&#110;&#100;&#105;&#116;&#105;&#111;&#110;&#115;&#47;\">Read More ><\/a><\/p>\n","protected":false},"author":17,"featured_media":1895,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"__cvm_playback_settings":[],"__cvm_video_id":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-1894","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general"],"acf":[],"aioseo_notices":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.8.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Motivational Disorders in Brain Conditions - Centre for Integrative Neuroscience and Neurodynamics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/research.reading.ac.uk\/cinn\/motivational-disorders-in-brain-conditions\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Motivational Disorders in Brain Conditions - Centre for Integrative Neuroscience and Neurodynamics\" \/>\n<meta property=\"og:description\" content=\"Professor Ciara McCabe\u00a0was included in a write up by\u00a0The Dana Foundation\u00a0on the BNA Festival of Neuroscience. Discussing research looking at how disorders of motivation affect a significant minority of people...Read More &gt;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/research.reading.ac.uk\/cinn\/motivational-disorders-in-brain-conditions\/\" \/>\n<meta property=\"og:site_name\" content=\"Centre for Integrative Neuroscience and Neurodynamics\" \/>\n<meta property=\"article:published_time\" content=\"2017-04-26T15:27:36+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-09-09T15:43:25+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/research.reading.ac.uk\/cinn\/wp-content\/uploads\/sites\/111\/CINN\/img_9943.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"750\" \/>\n\t<meta property=\"og:image:height\" content=\"450\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Tim Yates\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@UniRdg_CINN\" \/>\n<meta name=\"twitter:site\" content=\"@UniRdg_CINN\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Tim Yates\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/motivational-disorders-in-brain-conditions\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/motivational-disorders-in-brain-conditions\/\"},\"author\":{\"name\":\"Tim Yates\",\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/#\/schema\/person\/5692f00ff779064c7ff29399128d9cfd\"},\"headline\":\"Motivational Disorders in Brain Conditions\",\"datePublished\":\"2017-04-26T15:27:36+00:00\",\"dateModified\":\"2024-09-09T15:43:25+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/motivational-disorders-in-brain-conditions\/\"},\"wordCount\":310,\"publisher\":{\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/#organization\"},\"articleSection\":[\"General\"],\"inLanguage\":\"en-GB\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/motivational-disorders-in-brain-conditions\/\",\"url\":\"https:\/\/research.reading.ac.uk\/cinn\/motivational-disorders-in-brain-conditions\/\",\"name\":\"Motivational Disorders in Brain Conditions - 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