{"id":6736,"date":"1024-04-03T14:37:19","date_gmt":"1024-04-03T14:38:34","guid":{"rendered":"https:\/\/research.reading.ac.uk\/cinn\/?p=6736"},"modified":"2026-02-02T16:13:21","modified_gmt":"2026-02-02T16:13:21","slug":"genesis","status":"publish","type":"post","link":"https:\/\/research.reading.ac.uk\/cinn\/genesis\/","title":{"rendered":"GENESIS: Predicting outcomes to experimental surgery"},"content":{"rendered":"<p>[vc_row][vc_column width=&#8221;1\/4&#8243;][vc_single_image source=&#8221;featured_image&#8221; img_size=&#8221;full&#8221;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text]<\/p>\n<div class=\"wpb_column vc_column_container vc_col-sm-8\">\n<div class=\"vc_column-inner\">\n<div class=\"wpb_wrapper\">\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p>GENESIS stands for \u201cGenicular artery embolisation for osteoarthritis of the knee\u201d. This study is a interdisciplinary experiment to investigate the use of \u2019embolisation\u2019 as a surgical treatment for knee osteoarthritis (OA). However, this intervention (alongside all surgical interventions for OA) creates a subset of patients who do not experience the benefits of the surgery, have no pain relief, or in some instances, experience deterioration.<\/p>\n<p>In CINN, we will administer a neuropsychological assessment battery before the procedure, to attempt to identify predictive markers for clinical outcomes to embolisation. This assessment uses psychometric, sensory pain and neuroscientific approaches to profile each patient, and identify features of resilience and vulnerability within.<\/p>\n<p>This study is lead by <a href=\"https:\/\/research.reading.ac.uk\/cinn\/rich-harrison\/\">Dr Rich Harrison (rich.harrison@reading.ac.uk)<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column width=&#8221;1\/4&#8243;][vc_single_image source=&#8221;featured_image&#8221; img_size=&#8221;full&#8221;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text] GENESIS stands for \u201cGenicular artery embolisation for osteoarthritis of the knee\u201d. This study is a interdisciplinary experiment to investigate the use of \u2019embolisation\u2019 as a&#8230;<a class=\"read-more\" href=\"&#104;&#116;&#116;&#112;&#115;&#58;&#47;&#47;&#114;&#101;&#115;&#101;&#97;&#114;&#99;&#104;&#46;&#114;&#101;&#97;&#100;&#105;&#110;&#103;&#46;&#97;&#99;&#46;&#117;&#107;&#47;&#99;&#105;&#110;&#110;&#47;&#103;&#101;&#110;&#101;&#115;&#105;&#115;&#47;\">Read More ><\/a><\/p>\n","protected":false},"author":471,"featured_media":4886,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"__cvm_playback_settings":[],"__cvm_video_id":"","footnotes":""},"categories":[307,305],"tags":[],"class_list":["post-6736","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-completed","category-research-study"],"acf":[],"aioseo_notices":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.8.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>GENESIS: Predicting outcomes to experimental surgery - Centre for Integrative Neuroscience and Neurodynamics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/research.reading.ac.uk\/cinn\/genesis\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"GENESIS: Predicting outcomes to experimental surgery - Centre for Integrative Neuroscience and Neurodynamics\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column width=&#8221;1\/4&#8243;][vc_single_image source=&#8221;featured_image&#8221; img_size=&#8221;full&#8221;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text] GENESIS stands for \u201cGenicular artery embolisation for osteoarthritis of the knee\u201d. This study is a interdisciplinary experiment to investigate the use of \u2019embolisation\u2019 as a...Read More &gt;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/research.reading.ac.uk\/cinn\/genesis\/\" \/>\n<meta property=\"og:site_name\" content=\"Centre for Integrative Neuroscience and Neurodynamics\" \/>\n<meta property=\"article:published_time\" content=\"1024-04-03T14:38:34+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-02T16:13:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/research.reading.ac.uk\/cinn\/wp-content\/uploads\/sites\/111\/2020\/12\/Screenshot-2022-06-18-at-12.44.22-e1655556371917.png\" \/>\n\t<meta property=\"og:image:width\" content=\"355\" \/>\n\t<meta property=\"og:image:height\" content=\"200\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Anastasia Christakou\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@UniRdg_CINN\" \/>\n<meta name=\"twitter:site\" content=\"@UniRdg_CINN\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Anastasia Christakou\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/genesis\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/genesis\/\"},\"author\":{\"name\":\"Anastasia Christakou\",\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/#\/schema\/person\/22f15884f08b8fc93fb50e4cd1a519ec\"},\"headline\":\"GENESIS: Predicting outcomes to experimental surgery\",\"datePublished\":\"1024-04-03T14:38:34+00:00\",\"dateModified\":\"2026-02-02T16:13:21+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/genesis\/\"},\"wordCount\":156,\"publisher\":{\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/#organization\"},\"articleSection\":[\"Completed\",\"Research Study\"],\"inLanguage\":\"en-GB\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/genesis\/\",\"url\":\"https:\/\/research.reading.ac.uk\/cinn\/genesis\/\",\"name\":\"GENESIS: Predicting outcomes to experimental surgery - 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