{"id":7678,"date":"2022-04-29T13:13:30","date_gmt":"2022-04-29T12:13:30","guid":{"rendered":"https:\/\/research.reading.ac.uk\/cinn\/?p=7678"},"modified":"2026-04-29T13:21:20","modified_gmt":"2026-04-29T12:21:20","slug":"the-acute-and-chronic-effects-of-probiotic-supplementation-on-depressive-symptoms-and-neural-activation-prodep","status":"publish","type":"post","link":"https:\/\/research.reading.ac.uk\/cinn\/the-acute-and-chronic-effects-of-probiotic-supplementation-on-depressive-symptoms-and-neural-activation-prodep\/","title":{"rendered":"The Acute and Chronic Effects of Probiotic Supplementation on Depressive Symptoms and Neural Activation (PRODEP)"},"content":{"rendered":"<p>[vc_row][vc_column width=&#8221;1\/4&#8243;][vc_single_image source=&#8221;featured_image&#8221; img_size=&#8221;full&#8221;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text]This study aims to investigate the effects of probiotic supplementation on depressive symptoms, executive function, and neural activation. You will be required to attend 3 visits, each lasting between 2-3 hours. At each of these visits you will complete a number of mood questionnaires and two cognitive tasks, one of which will be done with EEG. These visits include a baseline test, 24-hour test, and a 16-week test. You will be asked to take a probiotic, or placebo, throughout the duration of the study.<\/p>\n<p><strong>Inclusion Criteria:<\/strong><\/p>\n<ul>\n<li>\u00a025-40 years old<\/li>\n<li>Experiencing mild-to-moderate depressive symptoms<\/li>\n<li>Right-handed<\/li>\n<\/ul>\n<p>If you think you would be eligible, and are interested in taking part, please email: v.amarallopessimoes@pgr.reading.ac.uk[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column width=&#8221;1\/4&#8243;][vc_single_image source=&#8221;featured_image&#8221; img_size=&#8221;full&#8221;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text]This study aims to investigate the effects of probiotic supplementation on depressive symptoms, executive function, and neural activation. You will be required to attend 3 visits,&#8230;<a class=\"read-more\" href=\"&#104;&#116;&#116;&#112;&#115;&#58;&#47;&#47;&#114;&#101;&#115;&#101;&#97;&#114;&#99;&#104;&#46;&#114;&#101;&#97;&#100;&#105;&#110;&#103;&#46;&#97;&#99;&#46;&#117;&#107;&#47;&#99;&#105;&#110;&#110;&#47;&#116;&#104;&#101;&#45;&#97;&#99;&#117;&#116;&#101;&#45;&#97;&#110;&#100;&#45;&#99;&#104;&#114;&#111;&#110;&#105;&#99;&#45;&#101;&#102;&#102;&#101;&#99;&#116;&#115;&#45;&#111;&#102;&#45;&#112;&#114;&#111;&#98;&#105;&#111;&#116;&#105;&#99;&#45;&#115;&#117;&#112;&#112;&#108;&#101;&#109;&#101;&#110;&#116;&#97;&#116;&#105;&#111;&#110;&#45;&#111;&#110;&#45;&#100;&#101;&#112;&#114;&#101;&#115;&#115;&#105;&#118;&#101;&#45;&#115;&#121;&#109;&#112;&#116;&#111;&#109;&#115;&#45;&#97;&#110;&#100;&#45;&#110;&#101;&#117;&#114;&#97;&#108;&#45;&#97;&#99;&#116;&#105;&#118;&#97;&#116;&#105;&#111;&#110;&#45;&#112;&#114;&#111;&#100;&#101;&#112;&#47;\">Read More ><\/a><\/p>\n","protected":false},"author":1140,"featured_media":7679,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"__cvm_playback_settings":[],"__cvm_video_id":"","footnotes":""},"categories":[306,305],"tags":[],"class_list":["post-7678","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ongoing","category-research-study"],"acf":[],"aioseo_notices":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.8.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The Acute and Chronic Effects of Probiotic Supplementation on Depressive Symptoms and Neural Activation (PRODEP) - Centre for Integrative Neuroscience and Neurodynamics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/research.reading.ac.uk\/cinn\/the-acute-and-chronic-effects-of-probiotic-supplementation-on-depressive-symptoms-and-neural-activation-prodep\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The Acute and Chronic Effects of Probiotic Supplementation on Depressive Symptoms and Neural Activation (PRODEP) - Centre for Integrative Neuroscience and Neurodynamics\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column width=&#8221;1\/4&#8243;][vc_single_image source=&#8221;featured_image&#8221; img_size=&#8221;full&#8221;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text]This study aims to investigate the effects of probiotic supplementation on depressive symptoms, executive function, and neural activation. You will be required to attend 3 visits,...Read More &gt;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/research.reading.ac.uk\/cinn\/the-acute-and-chronic-effects-of-probiotic-supplementation-on-depressive-symptoms-and-neural-activation-prodep\/\" \/>\n<meta property=\"og:site_name\" content=\"Centre for Integrative Neuroscience and Neurodynamics\" \/>\n<meta property=\"article:published_time\" content=\"2022-04-29T12:13:30+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-29T12:21:20+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/research.reading.ac.uk\/cinn\/wp-content\/uploads\/sites\/111\/2026\/04\/A-cartoon-of-small-creatures-in-a-small-intestine-AI-generated-content-may-be-incorrect_-e1777465374418.png\" \/>\n\t<meta property=\"og:image:width\" content=\"575\" \/>\n\t<meta property=\"og:image:height\" content=\"579\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Faye Davies\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@UniRdg_CINN\" \/>\n<meta name=\"twitter:site\" content=\"@UniRdg_CINN\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Faye Davies\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/the-acute-and-chronic-effects-of-probiotic-supplementation-on-depressive-symptoms-and-neural-activation-prodep\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/the-acute-and-chronic-effects-of-probiotic-supplementation-on-depressive-symptoms-and-neural-activation-prodep\/\"},\"author\":{\"name\":\"Faye Davies\",\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/#\/schema\/person\/637db7c913592733be7ceb07ee63927c\"},\"headline\":\"The Acute and Chronic Effects of Probiotic Supplementation on Depressive Symptoms and Neural Activation (PRODEP)\",\"datePublished\":\"2022-04-29T12:13:30+00:00\",\"dateModified\":\"2026-04-29T12:21:20+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/the-acute-and-chronic-effects-of-probiotic-supplementation-on-depressive-symptoms-and-neural-activation-prodep\/\"},\"wordCount\":158,\"publisher\":{\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/#organization\"},\"articleSection\":[\"Ongoing\",\"Research Study\"],\"inLanguage\":\"en-GB\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/research.reading.ac.uk\/cinn\/the-acute-and-chronic-effects-of-probiotic-supplementation-on-depressive-symptoms-and-neural-activation-prodep\/\",\"url\":\"https:\/\/research.reading.ac.uk\/cinn\/the-acute-and-chronic-effects-of-probiotic-supplementation-on-depressive-symptoms-and-neural-activation-prodep\/\",\"name\":\"The Acute and Chronic Effects of Probiotic Supplementation on Depressive Symptoms and Neural Activation (PRODEP) - 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