{"id":21595,"date":"2021-02-19T09:12:48","date_gmt":"2021-02-19T09:12:48","guid":{"rendered":"https:\/\/research.reading.ac.uk\/research-blog\/?p=21595"},"modified":"2021-02-19T09:12:48","modified_gmt":"2021-02-19T09:12:48","slug":"coronavirus-is-the-kent-variant-responsible-for-the-rise-in-cases-among-young-people-in-israel-and-italy","status":"publish","type":"post","link":"https:\/\/research.reading.ac.uk\/research-blog\/2021\/02\/19\/coronavirus-is-the-kent-variant-responsible-for-the-rise-in-cases-among-young-people-in-israel-and-italy\/","title":{"rendered":"Coronavirus: is the Kent variant responsible for the rise in cases among young people in Israel and Italy?"},"content":{"rendered":"

At the start of the pandemic, one of the first questions scientists asked was: \u201cWhat is the risk to children?\u201d Information emerging from China was that \u2013 pre-existing conditions aside \u2013 the younger you are, the lower your risk<\/a> of getting severe COVID. While children\u2019s lives have been taken by the coronavirus, the numbers are low<\/a>.<\/p>\n

This mirrors the situation seen with influenza. Children do get sick with that virus, but the effects on pre-teens, if any, are much less severe than they are for adults<\/a>. But that doesn\u2019t mean that flu in children is not a problem \u2013 quite the contrary.<\/p>\n

\"\"<\/p>\n

<\/p>\n

In the UK, children in primary school receive a flu vaccine that is sprayed up their noses<\/a>. This is not done primarily to protect them from the relatively mild symptoms they may get \u2013 although that will happen \u2013 it is to reduce the chances of them getting infected and becoming mobile virus factories, infecting the adults around them. A child\u2019s minor illness from flu could be lethal if transmitted to a grandparent.<\/p>\n

In the early days of the pandemic, this low level of disease in children of all ages led to some assumptions that it was because they rarely caught the virus. When evidence started to appear that, in fact, they did catch the virus, the question of whether they could pass it on to adults was raised.<\/p>\n

Knowing that children could be engines of virus spread caused some experts urged caution about declaring infection in pre-teens to not be a problem. While it was obvious from the numbers of people being admitted to hospital that childhood disease was far from the most pressing issue of the pandemic, the possibility that they might drive transmission was what caused schools to be closed.<\/p>\n

We\u2019re often told that most coronavirus spread occurs in private homes<\/a>, and that is true. But if the virus is prevented from entering the home in the first place, the whole household will be protected. Stopping a child bringing the virus home from school, having picked it up from their asymptomatic classmates, is one way of doing that.<\/p>\n

In the UK, there have been calls from politicians and teaching unions to vaccinate teachers<\/a> and open schools. But it is the risk to the wider community that causes closure, not the risk to staff.<\/p>\n

The Kent variant<\/strong><\/p>\n

With the advent of a worrying coronavirus known as the \u201cKent variant\u201d, which spreads rapidly, some doctors have noticed a higher frequency of infection in children<\/a>. Although numbers remain low, more infection in any group, regardless of their age, can be expected to translate into more illness and more hospital admissions.<\/p>\n

Paediatricians in Israel have reported increased infections in children<\/a>. But this is in a country that has vaccinated large numbers of its adult population with the Pfizer vaccine, which is not currently given to under-16s<\/a>. So it is unsurprising that children, as an entirely unvaccinated section of the population, should account for an increased proportion of Israel\u2019s coronavirus infections. It\u2019s possible that what is being seen would be mirrored, or maybe even exceeded, in the adults, had they not been vaccinated.<\/p>\n

But doctors in Italy, where the population is relatively lacking immunity, compared with Israel, have recently observed<\/a> high numbers of Kent variant infections in children, which seem to have found their way into adults.<\/p>\n

It remains unclear whether this was due to the reopening of schools, but it is tempting to speculate that this is the reason. Still, the observation that infection in children is leading to infection in adults, which is likely to cause more serious disease, is something that needs to be taken into consideration.<\/p>\n

Uncertain evidence<\/strong><\/p>\n

When the UK\u2019s health secretary, Matt Hancock, first reported this \u201cvariant of concern\u201d to the public, it prompted a lot of dismissive commentary from scientists and doctors. But as the quality and quantity of data increased, it became apparent that it is indeed\u00a0more transmissible<\/a>.<\/p>\n

The recent, uncertain suggestion that it might also be more lethal will either crystallise or fade away as more data is accumulated<\/a>.<\/p>\n

Neil Ferguson, a professor of mathematical biology at Imperial College London, said there is a hint<\/a>, in the available data, that the Kent variant \u201chas a higher propensity to infect children\u201d. But this is similarly uncertain and more data is needed.<\/p>\n

While an increase in infectiousness in children is, of course, nothing to be indifferent about, the biggest impact on our health will probably be from children acting as a vehicle to infect adults and cause illness in those for whom vaccination fails to provide protection.<\/p>\n

Simon Clarke is an Associate Professor in the Department of Biomedical Sciences.<\/p>\n

This article is republished from\u00a0The Conversation<\/a>\u00a0under a Creative Commons license.<\/p>\n","protected":false},"excerpt":{"rendered":"

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