{"id":23228,"date":"2021-12-22T09:25:19","date_gmt":"2021-12-22T09:25:19","guid":{"rendered":"https:\/\/research.reading.ac.uk\/research-blog\/?p=23228"},"modified":"2021-12-20T09:30:11","modified_gmt":"2021-12-20T09:30:11","slug":"coffees-health-benefits-arent-as-straightforward-as-they-seem-heres-why","status":"publish","type":"post","link":"https:\/\/research.reading.ac.uk\/research-blog\/2021\/12\/22\/coffees-health-benefits-arent-as-straightforward-as-they-seem-heres-why\/","title":{"rendered":"Coffee\u2019s health benefits aren\u2019t as straightforward as they seem \u2013 here\u2019s why"},"content":{"rendered":"<p>You\u2019ve probably heard it before: drinking coffee is good for your health. Studies have shown that drinking a moderate amount of coffee is associated with many health benefits, including a lower risk of developing <a href=\"https:\/\/www.acpjournals.org\/doi\/pdf\/10.7326\/0003-4819-140-1-200401060-00005\">type 2 diabetes<\/a> and <a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCULATIONAHA.113.005925?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%20%200pubmed\">cardiovascular disease<\/a>. But while these associations have been demonstrated many times, they don\u2019t actually prove that coffee reduces disease risk. In fact, proving that coffee is good for your health is complicated.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-23230 size-full\" src=\"https:\/\/research.reading.ac.uk\/research-blog\/wp-content\/uploads\/sites\/72\/2021\/12\/coffee-beans-g25c3feeda_640.jpg\" alt=\"\" width=\"640\" height=\"425\" srcset=\"https:\/\/research.reading.ac.uk\/research-blog\/wp-content\/uploads\/sites\/72\/2021\/12\/coffee-beans-g25c3feeda_640.jpg 640w, https:\/\/research.reading.ac.uk\/research-blog\/wp-content\/uploads\/sites\/72\/2021\/12\/coffee-beans-g25c3feeda_640-300x199.jpg 300w, https:\/\/research.reading.ac.uk\/research-blog\/wp-content\/uploads\/sites\/72\/2021\/12\/coffee-beans-g25c3feeda_640-272x182.jpg 272w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><!--more--><\/p>\n<p>While it\u2019s suggested that consuming three to five cups of coffee a day will provide <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0939475321002374#tbl3\">optimal health benefits<\/a>, it\u2019s not quite that straightforward. Coffee is chemically complex, containing many components that can affect your health in different ways.<\/p>\n<p>While caffeine is the most well-known compound in coffee, there is more to coffee than caffeine. Here are a few of the other compounds found in coffee that might affect your health.<\/p>\n<p><strong>Alkaloids.<\/strong> Aside from caffeine, trigonelline is another important alkaloid found in coffee. Trigonelline is less researched than caffeine, but research suggests that it may have health benefits, such as reducing the risk of <a href=\"https:\/\/care.diabetesjournals.org\/content\/diacare\/32\/6\/1023.full.pdf\">type 2 diabetes<\/a>.<\/p>\n<p><strong>Polyphenols.<\/strong> Some research shows that these compounds, which are found in many plants, including cocoa and blueberries, are good for your <a href=\"https:\/\/pdfs.semanticscholar.org\/8c23\/2f7a7744309e370e8ac25bafe01909c08a3d.pdf\">heart and blood vessels<\/a>, and may help to prevent neurodegenerative diseases such as <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0891584911005764?casa_token=IOJ2NHQy-vkAAAAA:LCRWlOmiFFzQvbNiq3g2bPjQIQv4sSlfiDp7-qNW7jzQdis4zwCufAgbdRfHzm9h1mYQwcBcU6U\">Alzheimer\u2019s<\/a>. Coffee predominantly contains a class of polyphenols called chlorogenic acids.<\/p>\n<p><strong>Diterpenes.<\/strong> Coffee contains two types of diterpenes \u2013 cafestol and kahweol \u2013 that make up coffee oil, the natural fatty substance released from coffee during brewing. Diterpenes may increase the risk of <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/epdf\/10.1002\/mnfr.200400109\">cardiovascular disease<\/a>.<\/p>\n<p><strong>Melanoidins.<\/strong> These compounds, which are produced at high temperatures during the roasting process, give roasted coffee its colour and provide the characteristic flavour and aroma of coffee. They may also have a prebiotic effect, meaning they increase the amount of <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mnfr.200500011\">beneficial bacteria in your gut<\/a>, which is important for overall health.<\/p>\n<p>The way your coffee is grown, brewed and served can all affect the compounds your coffee contains and hence the health benefits you might see.<\/p>\n<p>First, growing conditions can affect the levels of caffeine and chlorogenic acids the coffee contains. For example, coffee grown at <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0963996917307858\">high altitudes<\/a> will have both lower caffeine and chlorogenic acid content. The two types of coffee beans, <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2212429221004983?via%3Dihub#bib2\">arabica and robusta<\/a>, have also been shown to have different caffeine, chlorogenic acid and trigonelline levels. Although neither type has been shown to be more beneficial to health.<\/p>\n<p>Processing will also affect the coffee\u2019s <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8620865\/\">chemical composition<\/a>. For example, some coffee is decaffeinated. This is typically done before roasting, and depending on the decaffeination method, it may further affect other compounds. For example, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16417293\/\">small levels of chlorogenic<\/a> acids are lost during the decaffeination process.<\/p>\n<p>The extent that coffee is roasted is also key. The more severe the roasting, the more <a href=\"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jf800999a\">melanoidins formed<\/a> (and the more intense the flavour). But this lowers <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23993490\/\">chlorogenic acids<\/a> and <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S030881460500614X\">trigonelline<\/a> content.<\/p>\n<p>In the UK, instant coffee is the most commonly consumed type of coffee. This is typically freeze-dried. Research shows that instant coffee contains <a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2011\/FO\/c0fo00156b\">higher levels of melanoidins<\/a> per serving compared with filter coffee and espresso.<\/p>\n<p>How you <a href=\"https:\/\/www.nature.com\/articles\/s41598-017-18247-4\">prepare your coffee<\/a> will also affect its chemical composition. For example, <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0278691596001238\">boiled coffee<\/a> contains a higher level of diterpenes compared with filter coffee. Other factors \u2013 such as the amount of coffee used, how <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29230816\/\">finely it was ground<\/a>, water temperature and cup size \u2013 will also affect the coffee\u2019s chemical composition.<\/p>\n<h2><strong>Health effects<\/strong><\/h2>\n<p>Every compound has different effects on your health, which is why the way coffee is produced and brewed can be important.<\/p>\n<p>Chlorogenic acids, for example, are thought to reduce the risk of cardiovascular disease by improving the <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28012692\/\">function of your arteries<\/a>. There\u2019s also evidence they may reduce the <a href=\"https:\/\/care.diabetesjournals.org\/content\/diacare\/32\/6\/1023.full.pdf\">risk of type 2 diabetes<\/a> by controlling blood sugar spikes after eating.<\/p>\n<p>On the other hand, diterpenes have been shown to increase levels of low-density lipoprotein, a type of cholesterol associated with <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22713771\/\">cardiovascular disease<\/a>. While less research has focused on <a href=\"https:\/\/care.diabetesjournals.org\/content\/diacare\/32\/6\/1023.full.pdf\">trigonelline<\/a> and <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mnfr.200500011\">melanoidins<\/a>, some evidence suggests both may be good for your health.<\/p>\n<p>Adding cream, <a href=\"https:\/\/www.nhs.uk\/live-well\/eat-well\/how-does-sugar-in-our-diet-affect-our-health\">sugar<\/a> and syrup will change the nutritional content of your cup. Not only will they increase the calorie content, they may also increase your intake of saturated fats and sugars. Both of these are associated with increased risk of type 2 diabetes and cardiovascular disease and may counter the beneficial effects of the other compounds your cup of coffee contains.<\/p>\n<p>There\u2019s also evidence that people may respond differently to some of these compounds. Regularly drinking three to four cups of coffee daily has been shown to <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31900579\/\">build tolerance<\/a> to the blood pressure raising effects of caffeine. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29569539\/\">Genetics<\/a> may also play a role in how your body handles caffeine and other compounds.<\/p>\n<p>Increasing evidence also points to the gut microbiome as an important factor in determining what health effects coffee may have. For example, some research suggests the gut microbes play an important role in <a href=\"https:\/\/academic.oup.com\/jn\/article\/133\/6\/1853\/4688142\">chlorogenic acid metabolism<\/a>, and hence may determine if they will benefit your health or not.<\/p>\n<p>Researchers need to conduct large studies to confirm the findings of these smaller studies, which seem to show that coffee is good for your health. But in the meantime, minimise the sugar and cream you use in your coffee. And if you\u2019re in good health and aren\u2019t pregnant, continue to take a moderate approach to coffee consumption, choosing filter coffee where possible.<\/p>\n<p>Charlotte Mills is the Hugh Sinclair Lecturer in Nutritional Sciences and Ashley Hookings is a Doctoral Researcher in the Department of Human Nutrition.<\/p>\n<p>This article is republished from\u00a0<a href=\"https:\/\/theconversation.com\/coffees-health-benefits-arent-as-straightforward-as-they-seem-heres-why-172907\" target=\"_blank\" rel=\"noopener\">The Conversation<\/a>\u00a0under a Creative Commons license.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>You\u2019ve probably heard it before: drinking coffee is good for your health. Studies have shown that drinking a moderate amount of coffee is associated with many health benefits, including a&#8230;<a class=\"read-more\" href=\"&#104;&#116;&#116;&#112;&#115;&#58;&#47;&#47;&#114;&#101;&#115;&#101;&#97;&#114;&#99;&#104;&#46;&#114;&#101;&#97;&#100;&#105;&#110;&#103;&#46;&#97;&#99;&#46;&#117;&#107;&#47;&#114;&#101;&#115;&#101;&#97;&#114;&#99;&#104;&#45;&#98;&#108;&#111;&#103;&#47;&#50;&#48;&#50;&#49;&#47;&#49;&#50;&#47;&#50;&#50;&#47;&#99;&#111;&#102;&#102;&#101;&#101;&#115;&#45;&#104;&#101;&#97;&#108;&#116;&#104;&#45;&#98;&#101;&#110;&#101;&#102;&#105;&#116;&#115;&#45;&#97;&#114;&#101;&#110;&#116;&#45;&#97;&#115;&#45;&#115;&#116;&#114;&#97;&#105;&#103;&#104;&#116;&#102;&#111;&#114;&#119;&#97;&#114;&#100;&#45;&#97;&#115;&#45;&#116;&#104;&#101;&#121;&#45;&#115;&#101;&#101;&#109;&#45;&#104;&#101;&#114;&#101;&#115;&#45;&#119;&#104;&#121;&#47;\">Read More ><\/a><\/p>\n","protected":false},"author":276,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"__cvm_playback_settings":[],"__cvm_video_id":"","footnotes":""},"categories":[1785],"tags":[59,1903,1958,1611,423,1071],"class_list":["post-23228","post","type-post","status-publish","format-standard","hentry","category-agriculture-food-and-health","tag-alzheimers-disease","tag-cardiovascular-health","tag-coffee","tag-diabetes","tag-health-2","tag-human-nutrition"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.8.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Coffee\u2019s health benefits aren\u2019t as straightforward as they seem \u2013 here\u2019s why - Connecting Research<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/research.reading.ac.uk\/research-blog\/2021\/12\/22\/coffees-health-benefits-arent-as-straightforward-as-they-seem-heres-why\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Coffee\u2019s health benefits aren\u2019t as straightforward as they seem \u2013 here\u2019s why - Connecting Research\" \/>\n<meta property=\"og:description\" content=\"You\u2019ve probably heard it before: drinking coffee is good for your health. Studies have shown that drinking a moderate amount of coffee is associated with many health benefits, including a...Read More &gt;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/research.reading.ac.uk\/research-blog\/2021\/12\/22\/coffees-health-benefits-arent-as-straightforward-as-they-seem-heres-why\/\" \/>\n<meta property=\"og:site_name\" content=\"Connecting Research\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/theuniversityofreading\/\" \/>\n<meta property=\"article:published_time\" content=\"2021-12-22T09:25:19+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-12-20T09:30:11+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/research.reading.ac.uk\/research-blog\/wp-content\/uploads\/sites\/72\/2021\/12\/coffee-beans-g25c3feeda_640.jpg\" \/>\n<meta name=\"author\" content=\"Anna Frej\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@UniRdg_Research\" \/>\n<meta name=\"twitter:site\" content=\"@UniRdg_Research\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Anna Frej\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/research.reading.ac.uk\/research-blog\/2021\/12\/22\/coffees-health-benefits-arent-as-straightforward-as-they-seem-heres-why\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/research.reading.ac.uk\/research-blog\/2021\/12\/22\/coffees-health-benefits-arent-as-straightforward-as-they-seem-heres-why\/\"},\"author\":{\"name\":\"Anna Frej\",\"@id\":\"https:\/\/research.reading.ac.uk\/research-blog\/#\/schema\/person\/a83a75a4fb8e557ec1f4d6b12e6d5971\"},\"headline\":\"Coffee\u2019s health benefits aren\u2019t as straightforward as they seem \u2013 here\u2019s why\",\"datePublished\":\"2021-12-22T09:25:19+00:00\",\"dateModified\":\"2021-12-20T09:30:11+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/research.reading.ac.uk\/research-blog\/2021\/12\/22\/coffees-health-benefits-arent-as-straightforward-as-they-seem-heres-why\/\"},\"wordCount\":939,\"publisher\":{\"@id\":\"https:\/\/research.reading.ac.uk\/research-blog\/#organization\"},\"keywords\":[\"Alzheimer's disease\",\"cardiovascular health\",\"coffee\",\"diabetes\",\"health\",\"Human Nutrition\"],\"articleSection\":[\"Agriculture, Food &amp; 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