Huntington’s disease

Huntington’s disease health-related quality of life questionnaire (HDQoL)





Care-HD Horizon 2020 research programme


Ho AK. (2019). Huntington’s disease. In Degenerative Disorders of the Brain (pp. 88-115). Routledge.

Aubeeluck AV, Stupple EJ, Schofield M, Hughes A, Van der Meer L, Landwehrmeyer GB, & Ho AK. (2019). An International validation of a clinical tool to assess carers’ quality of life in Huntington’s Disease. Frontiers in Psychology, 10, 1658.

Maxan A, Mason S, Saint‐Pierre M, Smith E, Ho AK, Harrower T, Watts C, Tai Y, Pavese N, Savage JC & Tremblay MÈ. (2018). Outcome of cell suspension allografts in a patient with Huntington’s disease. Annals of Neurology, 84(6), pp.950-956.

Mestre TA, Busse M, Davis AM, Quinn L, Rodrigues FB, Burgunder JM, Carlozzi NE, Walker F, Ho AK, Sampaio C. & Goetz CG. (2018). Rating scales and performance‐based measures for assessment of functional ability in Huntington’s disease: critique and recommendations. Movement Disorders Clinical Practice, 5(4), pp.361-372.

Barker RA, Mason SL, Harrower TP, Swain RA, Ho AK, Sahakian BJ, Mathur R, Elneil S, Thornton S, Hurrelbrink C. & Armstrong RJ. (2013). The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington’s disease. Journal of Neurology, Neurosurgery & Psychiatry, 84(6), pp.657-665.

Vaccarino AL, Sills T, Anderson KE, Borowsky B, Craufurd D, Giuliano J, Goodman L, Guttman M, Kupchak P, Ho AK, Paulsen JS, C Stout J, van Kammen DP, Evans K. (2011). Assessment of Cognitive Symptoms in Prodromal and Early Huntington Disease. PLoS Curr, Oct 25;3:RRN1250.

Vaccarino AL, Sills T, Anderson KE, Endicott J, Giuliano J, Guttman M, Ho AK, Kupchak P, Paulsen JS, Warner JH, Williams J, Evans K. (2011). Assessment of Day-to-Day Functioning in Prodromal and Early Huntington Disease. PLoS Curr, Sep 12;3:RRN1262.

Ho AK, Hocaoglu MB; European Huntington’s Disease Network Quality of Life Working Group. (2011). Impact of Huntington’s across the entire disease spectrum: the phases and stages of disease from the patient perspective. Clinical Genetics, Sep;80(3):235-9.

Vaccarino AL, Anderson KE, Borowsky B, Coccaro E, Craufurd D, Endicott J, Giuliano J, Groves M, Guttman M, Ho AK, Kupchak P, Paulsen JS, Stanford MS, van Kammen DP, Watson D, Wu KD, Evans K. (2011). Assessing Behavioural Manifestations Prior to Clinical Diagnosis of Huntington Disease: “Anger and Irritability” and “Obsessions and Compulsions”. PLoS Curr, Jul 11;3:RRN1241.

Vaccarino AL, Sills T, Anderson KE, Bachoud-Lévi AC, Borowsky B, Craufurd D, Duff K, Giuliano J, Groves M, Guttman M, Kupchak P, Ho AK, Paulsen JS, Pedersen KF, van Duijn E, van Kammen DP, Evans K. (2011). Assessment of Depression, Anxiety and Apathy in Prodromal and Early Huntington Disease. PLoS Curr, Jun 17;3:RRN1242.

Vaccarino AL, Sills T, Anderson KE, Biglan K, Borowsky B, Giuliano J, Guttman M, Ho AK, Kennard C, Kupchak P, Landwehrmeyer GB, Michell A, Paulsen JS, Reilmann R, van Kammen DP, Warner JH, Evans K. (2011). Assessment of Motor Symptoms and Functional Impact in Prodromal and Early Huntington Disease. PLoS Curr, Jun 14;2:RRN1244.

Vaccarino AL, Anderson K, Borowsky B, Duff K, Giuliano J, Guttman M, Ho AK, Orth M, Paulsen JS, Sills T, van Kammen DP, Evans KR; PREDICT-HD and REGISTRY Investigators Coordinators. (2011). An item response analysis of the motor and behavioural subscales of the unified Huntington’s disease rating scale in huntington disease gene expansion carriers. Movement Disorders, Apr;26(5):877-84.

Orth M, Handley OJ, Schwenke C, Dunnett SB, Craufurd D, Ho AK, Wild E, Tabrizi SJ, Landwehrmeyer GB; Investigators of the European Huntington’s Disease Network. (2010). Observing Huntington’s Disease: the European Huntington’s Disease Network’s REGISTRY. PLoS Curr, Sep 28;2.

Mason SL, Wijeyekoon R, Swain R, Ho AK, Smith EL, Sahakian B, Barker RA. (2010). Cognitive follow up of a small cohort of Huntington’s disease patients over a 5 year period. PLoS Curr, Sep 7;2. pii: RRN1174.

Robbins AO, Ho, AK, Barker RA. (2006). Weight changes in Huntington’s disease. European Journal of Neurology,  Aug;13(8):e7.

Pavese N, Gerhard A, Tai YF, Ho, AK, Turkheimer F, Barker RA, Brooks DJ, Piccini P. (2006). Microglial activation correlates with severity in Huntington disease: a clinical and PET study. Neurology, Jun 13;66(11):1638-43.

Ho, AK, Robbins AO, Barker RA. (2006). Huntington’s disease patients have selective problems with insight. Movement Disorders, Mar;21(3):385-9. PubMed PMID: 16211608.

Ho, AK, Sahakian BJ, Robbins TW, Barker RA. (2004). Random number generation in patients with symptomatic and presymptomatic Huntington’s disease. Cognitive and Behavioural Neurology, Dec;17(4):208-12.

Ho, AK, Nestor PJ, Williams GB, Bradshaw JL, Sahakian BJ, Robbins TW, Barker RA. (2004). Pseudo-neglect in Huntington’s disease correlates with decreased angular gyrus density. Neuroreport, Apr 29;15(6):1061-4.

Ho, AK, Sahakian BJ, Brown RG, Barker RA, Hodges JR, Ané MN, Snowden J, Thompson J, Esmonde T, Gentry R, Moore JW, Bodner T; NEST-HD Consortium. (2003). Profile of cognitive progression in early Huntington’s disease. Neurology, Dec 23;61(12):1702-6.

Ho, AK, Manly T, Nestor PJ, Sahakian BJ, Bak TH, Robbins TW, Rosser AE, Barker RA. (2003). A case of unilateral neglect in Huntington’s disease. Neurocase, Jun;9(3):261-73.

Pavese N, Andrews TC, Brooks DJ, Ho AK, Rosser AE, Barker RA, Robbins TW, Sahakian BJ, Dunnett SB, Piccini P. (2003). Progressive striatal and cortical dopamine receptor dysfunction in Huntington’s disease: a PET study. Brain, May;126(Pt 5):1127-35.

Rosser AE, Barker RA, Harrower T, Watts C, Farrington M, Ho, AK, Burnstein RM, Menon DK, Gillard JH, Pickard J, Dunnett SB; NEST-UK. (2002). Unilateral transplantation of human primary fetal tissue in four patients with Huntington’s disease: NEST-UK safety report ISRCTN no 36485475. Journal of Neurology Neurosurgery and Psychiatry, Dec;73(6):678-85.