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Pain is a complex cognitive and emotional experience, which means that understanding the structure of our pain experience is far from easy. Our beliefs and expectations about pain alter perceptual, emotional and behavioural responses and, as such, can play a critical role in adapting to long term pain conditions. The symposium will consider pain’s meaning, how this shapes the experience of the individual in pain and how this, in turn, shapes their interactions with the environment. We will take an inter-disciplinary approach to these questions, drawing from Philosophy, Anthropology, Psychology and Neuroscience. We will also attempt to translate these perspectives into the clinical domain. The second day will be organised as an interactive discussion led by Dr. Salomons, Dr. Ravindran, and Dr. Thacker, examining how our understanding of pain-related beliefs and expectations might be integrated into clinical practice.